Validation of the Spartan RXCYP2C19 Genotyping Assay Utilizing Blood Samples

The antiplatelet agent clopidogrel, a prodrug that requires bioactivation through the cytochrome P450 2C19 (CYP2C19) enzyme, is commonly prescribed post‐percutaneous coronary intervention (PCI). Genetic variation in CYP2C19 contributes to individual variability in clopidogrel response, and can lead...

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Bibliographic Details
Main Authors: Brittney H. Davis, Gina DeFrank, Nita A. Limdi, Shuko Harada
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12714