Adenosine Depletion as A New Strategy to Decrease Glioblastoma Stem-Like Cells Aggressiveness

Adenosine Depletion as A New Strategy to Decrease Glioblastoma Stem-Like Cells Aggressiveness

Glioblastoma is the brain tumor with the worst prognosis. This is mainly due to a cell subpopulation with an extremely aggressive potential, called glioblastoma stem-like cells (GSCs). These cells produce high levels of extracellular adenosine, which are increased even more under hypoxic conditions....

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Bibliographic Details
Main Authors: Ignacio Niechi, Atenea Uribe-Ojeda, José Ignacio Erices, Ángelo Torres, Daniel Uribe, José Dellis Rocha, Pamela Silva, Hans G. Richter, Rody San Martín, Claudia Quezada
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
glioblastoma
adenosine
invasiveness
stemness
adenosine deaminase
Online Access:https://www.mdpi.com/2073-4409/8/11/1353

Internet

https://www.mdpi.com/2073-4409/8/11/1353

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