Safety and immunogenicity of an HIV adenoviral vector boost after DNA plasmid vaccine prime by route of administration: a randomized clinical trial.

Safety and immunogenicity of an HIV adenoviral vector boost after DNA plasmid vaccine prime by route of administration: a randomized clinical trial.

In the development of HIV vaccines, improving immunogenicity while maintaining safety is critical. Route of administration can be an important factor.This multicenter, open-label, randomized trial, HVTN 069, compared routes of administration on safety and immunogenicity of a DNA vaccine prime given...

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Bibliographic Details
Main Authors: Beryl A Koblin, Martin Casapia, Cecilia Morgan, Li Qin, Zhixue Maggie Wang, Olivier D Defawe, Lindsey Baden, Paul Goepfert, Georgia D Tomaras, David C Montefiori, M Juliana McElrath, Lilian Saavedra, Chuen-Yen Lau, Barney S Graham, NIAID HIV Vaccine Trials Network
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3171485?pdf=render

Internet

http://europepmc.org/articles/PMC3171485?pdf=render

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