Development of retroviral vectors for tissue-restricted expression in chicken embryonic gonads.

The chicken embryo has long been a useful model organism for studying development, including sex determination and gonadal differentiation. However, manipulating gene expression specifically in the embryonic avian gonad has been difficult. The viral vector RCASBP can be readily used for embryo-wide...

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Bibliographic Details
Main Authors: Luke S Lambeth, Thomas Ohnesorg, David M Cummins, Andrew H Sinclair, Craig A Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4086957?pdf=render