Silica Nanoparticles Provoke Cell Death Independent of p53 and BAX in Human Colon Cancer Cells

Silica Nanoparticles Provoke Cell Death Independent of p53 and BAX in Human Colon Cancer Cells

Several in vitro studies have suggested that silica nanoparticles (NPs) might induce adverse effects in gut cells. Here, we used the human colon cancer epithelial cell line HCT116 to study the potential cytotoxic effects of ingested silica NPs in the presence or absence of serum. Furthermore, we eva...

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Bibliographic Details
Main Authors: Susanne Fritsch-Decker, Zhen An, Jin Yan, Iris Hansjosten, Marco Al-Rawi, Ravindra Peravali, Silvia Diabaté, Carsten Weiss
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Nanomaterials
Subjects:
synthetic amorphous silica
nanoparticles
colon cells
in vitro toxicity
cell death
Online Access:https://www.mdpi.com/2079-4991/9/8/1172

Internet

https://www.mdpi.com/2079-4991/9/8/1172

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