High mobilization of CD133+/CD34+ cells expressing HIF-1α and SDF-1α in septic abdominal surgical patients

High mobilization of CD133+/CD34+ cells expressing HIF-1α and SDF-1α in septic abdominal surgical patients

Abstract Background The control of endothelial progenitor cells (CD133+/CD34+ EPCs) migrating from bone marrow to peripheral blood is not completely understood. Emerging evidence suggests that stromal cell-derived factor-1α (SDF-1α) mediates egression of EPCs from bone marrow, while the hypoxia indu...

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Bibliographic Details
Main Authors: Antonella Cotoia, Olga Cela, Gaetano Palumbo, Sabrina Altamura, Flavia Marchese, Nicoletta Mangialetto, Daniela La Bella, Vincenzo Lizzi, Nazzareno Capitanio, Gilda Cinnella
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Anesthesiology
Subjects:
Endothelial progenitor cells
Hypoxia inducible factor-1α
Stromal cell-derived factor-1α
Sepsis
Postoperative abdominal laparoscopic patients
Hematopoietic stem cells
Online Access:http://link.springer.com/article/10.1186/s12871-020-01068-w

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http://link.springer.com/article/10.1186/s12871-020-01068-w

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