Consuming Genistein Improves Survival Rates in the Absence of Laxative in ΔF508-CF Female Mice

Genistein is a naturally occurring isoflavone found in soy. Genistein has been shown to increase the open probability of the most common cystic fibrosis (CF) disease-associated mutation, ∆F508-CFTR. Mice homozygous for the ∆F508 mutation are characterized with severe intestinal disease and require c...

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Bibliographic Details
Main Authors: Ryan Lord, Nathan Fairbourn, Charisma Mylavarapu, Ammer Dbeis, Taylor Bowman, Archana Chandrashekar, Tatum Banayat, Craig A. Hodges, Layla Al-Nakkash
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/10/10/1418