S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model.

S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model.

Our previous study presented evidence that the inflammation-related S100A9 gene is significantly upregulated in the brains of Alzheimer's disease (AD) animal models and human AD patients. In addition, experiments have shown that knockdown of S100A9 expression improves cognition function in AD m...

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Bibliographic Details
Main Authors: Hee Jin Kim, Keun-A Chang, Tae-Young Ha, Jeonga Kim, Sungji Ha, Ki-Young Shin, Cheil Moon, Wolfgang Nacken, Hye-Sun Kim, Yoo-Hun Suh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3934881?pdf=render

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http://europepmc.org/articles/PMC3934881?pdf=render

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