Autonomous glucose metabolic reprogramming of tumour cells under hypoxia: opportunities for targeted therapy

Autonomous glucose metabolic reprogramming of tumour cells under hypoxia: opportunities for targeted therapy

Abstract Molecular oxygen (O2) is a universal electron acceptor that is eventually synthesized into ATP in the mitochondrial respiratory chain of all metazoans. Therefore, hypoxia biology has become an organizational principle of cell evolution, metabolism and pathology. Hypoxia-inducible factor (HI...

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Bibliographic Details
Main Authors: Mingyao Huang, Liang Yang, Xueqiang Peng, Shibo Wei, Qing Fan, Shuo Yang, Xinyu Li, Bowen Li, Hongyuan Jin, Bo Wu, Jingang Liu, Hangyu Li
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Hypoxia
Tumour
Glucose
Metabolic reprogramming
Online Access:http://link.springer.com/article/10.1186/s13046-020-01698-5

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http://link.springer.com/article/10.1186/s13046-020-01698-5

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