Role of mitochondrial dysfunction and dysregulation of Ca2+ homeostasis in the pathophysiology of insulin resistance and type 2 diabetes
Abstract Metabolic diseases such as obesity, type 2 diabetes (T2D) and insulin resistance have attracted great attention from biomedical researchers and clinicians because of the astonishing increase in its prevalence. Decrease in the capacity of oxidative metabolism and mitochondrial dysfunction ar...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-09-01
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Series: | Journal of Biomedical Science |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12929-017-0375-3 |