Microglia Induce PDGFRB Expression in Glioma Cells to Enhance Their Migratory Capacity

Microglia Induce PDGFRB Expression in Glioma Cells to Enhance Their Migratory Capacity

Summary: High-grade gliomas (HGGs) are the most aggressive and invasive primary brain tumors. The platelet-derived growth factor (PDGF) signaling pathway drives HGG progression, and enhanced expression of PDGF receptors (PDGFRs) is a well-established aberration in a subset of glioblastomas (GBMs). P...

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Bibliographic Details
Main Authors: Tatjana Wallmann, Xing-Mei Zhang, Majken Wallerius, Sara Bolin, Anne-Laure Joly, Caroline Sobocki, Lina Leiss, Yiwen Jiang, Jonas Bergh, Eric C. Holland, Per Ø. Enger, John Andersson, Fredrik J. Swartling, Hrvoje Miletic, Lene Uhrbom, Robert A. Harris, Charlotte Rolny
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218301706

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http://www.sciencedirect.com/science/article/pii/S2589004218301706

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