Analysis of Topological Parameters of Complex Disease Genes Reveals the Importance of Location in a Biomolecular Network

Network biology and medicine provide unprecedented opportunities and challenges for deciphering disease mechanisms from integrative viewpoints. The disease genes and their products perform their dysfunctions via physical and biochemical interactions in the form of a molecular network. The topologica...

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Bibliographic Details
Main Authors: Xiaohui Zhao, Zhi-Ping Liu
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/10/2/143