Flavonoids with M1 Muscarinic Acetylcholine Receptor Binding Activity

Muscarinic acetylcholine receptor-active compounds have potential for the treatment of Alzheimer’s disease. In this study, a series of natural and synthetic flavones and flavonols was assayed in vitro for their ability to inhibit radioligand binding at human cloned M1 muscarinic receptors. Several c...

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Bibliographic Details
Main Authors: Meyyammai Swaminathan, Chin Fei Chee, Sek Peng Chin, Michael J. C. Buckle, Noorsaadah Abd. Rahman, Stephen W. Doughty, Lip Yong Chung
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/7/8933