Does necroptosis have a crucial role in hepatic ischemia-reperfusion injury?

Previous studies have demonstrated protective effects of anti-receptor interacting protein kinase 1 (RIP1), a key necroptosis molecule. However, it is uncertain whether necroptosis has a crucial role in hepatic IR injury. Therefore, we evaluated the role of necroptosis in hepatic IR injury.The IR mi...

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Bibliographic Details
Main Authors: Waqar K Saeed, Dae Won Jun, Kiseok Jang, Yeon Ji Chae, Jai Sun Lee, Hyeon Tae Kang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5619711?pdf=render