Training rhesus macaques to take daily oral antiretroviral therapy for preclinical evaluation of HIV prevention and treatment strategies.

<h4>Background</h4>Macaque models of simian or simian/human immunodeficiency virus (SIV or SHIV) infection are critical for the evaluation of antiretroviral (ARV)-based HIV treatment and prevention strategies. However, modelling human oral ARV administration is logistically challenging a...

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Bibliographic Details
Main Authors: Michele B Daly, April M Clayton, Susan Ruone, James Mitchell, Chuong Dinh, Angela Holder, Julian Jolly, J Gerardo García-Lerma, James L Weed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225146