Comparative immunogenicity and protective capacity of two Dengue-4 vaccine candidates based on P64k-envelope domain III

In this work we compared, in the same immunization schedule in mice, two vaccine candidates against Dengue-4 based on the envelope protein domain III and the carrier P64k. Their molecular and antigenic features, immunogenicity and protective capacity in the viral encephalitis murine model are assess...

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Bibliographic Details
Main Authors: Laura Lazo, Lázaro Gil, Aída Zulueta, Iris Valdés, Yordanka Soria, Yaremis Romero, Gerardo Guillén, Lisset Hermida
Format: Article
Language:English
Published: Elfos Scientiae
Series:Biotecnología Aplicada
Subjects:
Online Access:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522009000400006&lng=en&tlng=en