Compartmentalization of HP1 Proteins in Pluripotency Acquisition and Maintenance

Summary: The heterochromatin protein 1 (HP1) family is involved in various functions with maintenance of chromatin structure. During murine somatic cell reprogramming, we find that early depletion of HP1γ reduces the generation of induced pluripotent stem cells, while late depletion enhances the pro...

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Bibliographic Details
Main Authors: Nur Zafirah Zaidan, Kolin J. Walker, Jaime E. Brown, Leah V. Schaffer, Mark Scalf, Michael R. Shortreed, Gopal Iyer, Lloyd M. Smith, Rupa Sridharan
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117305647