Astaxanthin Protects Retinal Photoreceptor Cells against High Glucose-Induced Oxidative Stress by Induction of Antioxidant Enzymes via the PI3K/Akt/Nrf2 Pathway

Astaxanthin Protects Retinal Photoreceptor Cells against High Glucose-Induced Oxidative Stress by Induction of Antioxidant Enzymes via the PI3K/Akt/Nrf2 Pathway

Diabetic retinopathy (DR) is a major microvascular complication that can lead to severe visual impairment in patients with diabetes. The elevated oxidative stress and increased reactive oxygen species (ROS) production induced by hyperglycemia have been reported to play an important role in the compl...

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Bibliographic Details
Main Authors: Tso-Ting Lai, Chung-May Yang, Chang-Hao Yang
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antioxidants
Subjects:
diabetic retinopathy
hyperglycemia
oxidative stress
astaxanthin
carotenoid
reactive oxygen species
Online Access:https://www.mdpi.com/2076-3921/9/8/729

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https://www.mdpi.com/2076-3921/9/8/729

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