Quetiapine has an additive effect to triiodothyronine in inducing differentiation of oligodendrocyte precursor cells through induction of cholesterol biosynthesis.

Quetiapine has an additive effect to triiodothyronine in inducing differentiation of oligodendrocyte precursor cells through induction of cholesterol biosynthesis.

Multiple sclerosis (MS) is characterized by demyelinated lesions in the central nervous system. Destruction of myelin and secondary damage to axons and neurons leads to significant disability, particularly in people with progressive MS. Accumulating evidence suggests that the potential for myelin re...

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Bibliographic Details
Main Authors: Jaime Gonzalez Cardona, Matthew D Smith, Jingya Wang, Leslie Kirby, Jason T Schott, Todd Davidson, Jodi L Karnell, Katharine A Whartenby, Peter A Calabresi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221747

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https://doi.org/10.1371/journal.pone.0221747

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