Tetramethylpyrazine Ameliorates Peritoneal Angiogenesis by Regulating VEGF/Hippo/YAP Signaling

Tetramethylpyrazine Ameliorates Peritoneal Angiogenesis by Regulating VEGF/Hippo/YAP Signaling

Angiogenesis of human peritoneal vascular endothelial cells (HPVECs), linked to vascular endothelial growth factor (VEGF)/VEGF receptor 2 (VEGFR2) signaling, is a complication of peritoneal fibrosis (PF). Hippo/YAP signaling interacts with VEGF/VEGFR2 signaling, but the effect on peritoneal angiogen...

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Bibliographic Details
Main Authors: Xiaolin Zhu, Yun Shan, Manshu Yu, Jun Shi, Lei Tang, Huimin Cao, Meixiao Sheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
peritoneal fibrosis
peritoneal angiogenesis
peritoneal vascular endothelial cells
YAP
Golgi
tetramethylpyrazine
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.649581/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.649581/full

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