Novel Frog Skin-Derived Peptide Dermaseptin-PP for Lung Cancer Treatment: In vitro/vivo Evaluation and Anti-tumor Mechanisms Study

Novel Frog Skin-Derived Peptide Dermaseptin-PP for Lung Cancer Treatment: In vitro/vivo Evaluation and Anti-tumor Mechanisms Study

Lung cancer is the major cause of cancer deaths worldwide, and it has the highest incidence and mortality rate of any cancer among men and women in China. The first-line therapy for lung cancer treatment is platinum-based chemotherapy drugs such as cisplatin. However, the application of present chem...

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Bibliographic Details
Main Authors: Ziyi Dong, Haiyan Hu, Xianglong Yu, Li Tan, Chengbang Ma, Xinping Xi, Lei Li, Lei Wang, Mei Zhou, Tianbao Chen, Shouying Du, Yang Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Chemistry
Subjects:
novel peptide discovery
molecular cloning
peptide synthesis
anti-lung cancer
membrane destruction
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00476/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2020.00476/full

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