Use of DNA Microarray and Small Animal Positron Emission Tomography in Preclinical Drug Evaluation of RAF265, a Novel B-Raf/VEGFR-2 Inhibitor

Positron emission tomography (PET) imaging has become a useful tool for assessing early biologic response to cancer therapy and may be particularly useful in the development of new cancer therapeutics. RAF265, a novel B-Raf/vascular endothelial growth factor receptor-2 inhibitor, was evaluated in t...

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Bibliographic Details
Main Authors: Jeffrey R. Tseng, Darrin Stuart, Kimberly Aardalen, Angelo Kaplan, Natasha Aziz, Nicholas P. Hughes, Sanjiv S. Gambhir
Format: Article
Language:English
Published: Elsevier 2011-03-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800746