Refining the reaction mechanism of O2 towards its co-substrate in cofactor-free dioxygenases
Cofactor-less oxygenases perform challenging catalytic reactions between singlet co-substrates and triplet oxygen, in spite of apparently violating the spin-conservation rule. In 1-H-3-hydroxy-4-oxoquinaldine-2,4-dioxygenase, the active site has been suggested by quantum chemical computations to fin...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PeerJ Inc.
2016-12-01
|
| Series: | PeerJ |
| Subjects: | |
| Online Access: | https://peerj.com/articles/2805.pdf |