Combination blockade of KLRG1 and PD-1 promotes immune control of local and disseminated cancers

Checkpoint blockade therapy is effective against many cancers; however, new targets need to be identified to treat patients who do not respond to current treatment or demonstrate immune escape. Here, we showed that blocking the inhibitory receptor Killer cell lectin-like receptor G1 (KLRG1) enhances...

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Bibliographic Details
Main Authors: Angela Tata, Garvin Dodard, Céline Fugère, Corinne Leget, Mélody Ors, Benjamin Rossi, Eric Vivier, Laurent Brossay
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2021.1933808