Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs

Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs

Lung disease is a major cause of death in the United States, with current therapeutic approaches serving only to manage symptoms. The most common chronic and life-threatening genetic disease of the lung is cystic fibrosis (CF) caused by mutations in the cystic fibrosis transmembrane regulator (CFTR)...

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Bibliographic Details
Main Authors: Amy L. Firth, Tushar Menon, Gregory S. Parker, Susan J. Qualls, Benjamin M. Lewis, Eugene Ke, Carl T. Dargitz, Rebecca Wright, Ajai Khanna, Fred H. Gage, Inder M. Verma
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715008529

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http://www.sciencedirect.com/science/article/pii/S2211124715008529

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