In Vitro Evaluation of No-Carrier-Added Radiolabeled Cisplatin ([<sup>189, 191</sup>Pt]cisplatin) Emitting Auger Electrons

In Vitro Evaluation of No-Carrier-Added Radiolabeled Cisplatin ([<sup>189, 191</sup>Pt]cisplatin) Emitting Auger Electrons

Due to their short-range (2–500 nm), Auger electrons (Auger <i>e<sup>−</sup></i>) have the potential to induce nano-scale physiochemical damage to biomolecules. Although DNA is the primary target of Auger <i>e</i><sup>−</sup>, it remains challenging to...

Full description

Bibliographic Details
Main Authors: Honoka Obata, Atsushi B. Tsuji, Hitomi Sudo, Aya Sugyo, Katsuyuki Minegishi, Kotaro Nagatsu, Mikako Ogawa, Ming-Rong Zhang
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
Auger electron
cisplatin
<sup>191</sup>Pt
<sup>189</sup>Pt
radio-drug
DNA double-strand break
Online Access:https://www.mdpi.com/1422-0067/22/9/4622

Internet

https://www.mdpi.com/1422-0067/22/9/4622

Similar Items