Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling

Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling

Abstract Background Kaempferol, a natural flavonoid, exhibits anticancer properties by scavenging reactive oxygen species (ROS). However, increasing evidence has demonstrated that, under certain conditions, kaempferol can inhibit tumor growth by upregulating ROS levels. In this study, we aimed to in...

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Bibliographic Details
Main Authors: Fengjiao Wang, Lai Wang, Chao Qu, Lianyu Chen, Yawen Geng, Chienshan Cheng, Shulin Yu, Dan Wang, Lina Yang, Zhiqiang Meng, Zhen Chen
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Cancer
Subjects:
Pancreatic cancer
Kaempferol
Tissue transglutaminase
ROS
Apoptosis
Biomarker
Online Access:https://doi.org/10.1186/s12885-021-08158-z

Internet

https://doi.org/10.1186/s12885-021-08158-z

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