Preparation of RGD-modified Long Circulating Liposome Loading Matrine, and its in vitro Anti-cancer Effects

<p><b>Aim: </b>To prepare RGD-modified long circulating liposome (LCL) loading matrine (RGD-M-LCL) to improve the tumor-targeting and efficacy of matrine. <b>Methods: </b>LCL which was prepared with HSPC, cholesterol, DSPE-PEG2000 and DSPE-PEG-MAL was modified with an R...

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Bibliographic Details
Main Author: Xiao-yan Liu, Li-ming Ruan, Wei-wei Mao, Jin-Qiang Wang, You-qing Shen, Mei-hua Sui
Format: Article
Language:English
Published: Ivyspring International Publisher 2010-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v07p0197.htm