Optical imaging of disseminated leukemia models in mice with near-infrared probe conjugated to a monoclonal antibody.

Optical imaging of disseminated leukemia models in mice with near-infrared probe conjugated to a monoclonal antibody.

BACKGROUND: The assessment of anticancer agents to treat leukemia needs to have animal models closer to the human pathology such as implantation in immunodeficient mice of leukemic cells from patient samples. A sensitive and early detection of tumor cells in these orthotopic models is a prerequisite...

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Bibliographic Details
Main Authors: Sabrina Pesnel, Arnaud Pillon, Laurent Créancier, Stéphanie Lerondel, Alain Le Pape, Christian Recher, Cécile Demur, Nicolas Guilbaud, Anna Kruczynski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3267751?pdf=render

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http://europepmc.org/articles/PMC3267751?pdf=render

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