Safety and efficacy of using heat-killed Lactobacillus plantarum L-137: High-dose and long-term use effects on immune-related safety and intestinal bacterial flora

Safety and efficacy of using heat-killed Lactobacillus plantarum L-137: High-dose and long-term use effects on immune-related safety and intestinal bacterial flora

Heat-killed Lactobacillus plantarum L-137 (HK L-137) promotes immune function in animals. In healthy people, T-cell proliferation was shown to be enhanced by taking 10 mg HK L-137 daily for 12 weeks. However, the safety and efficacy of higher doses or longer treatments have not yet been investigated...

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Bibliographic Details
Main Authors: Hiroko Nakai, Shinji Murosaki, Yoshihiro Yamamoto, Michiko Furutani, Rumiko Matsuoka, Yoshitaka Hirose
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Journal of Immunotoxicology
Subjects:
heat-killed bacteria
safety
adverse event
lactobacillus plantarum l-137
t-cell proliferation
microbiota
firmicutes
bacteroidetes
short-chain fatty acids
Online Access:http://dx.doi.org/10.1080/1547691X.2021.1979698

Internet

http://dx.doi.org/10.1080/1547691X.2021.1979698

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