Screening for precancerous anal lesions with P16/Ki67 immunostaining in HIV-infected MSM.

Screening for precancerous anal lesions with P16/Ki67 immunostaining in HIV-infected MSM.

Screening of anal cancer in HIV-infected MSM with anal cytology results in high rates of false positive results and elevated burden of high-resolution anoscopies. High-risk HPV up-regulates p16 and Ki67 expression in epithelial cells. We assessed the usefulness of P16/Ki-67 immunostaining cytology f...

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Bibliographic Details
Main Authors: Sergio Serrano-Villar, Beatriz Hernández-Novoa, Amparo de Benito, Jorge Del Romero, Antonio Ocampo, José Ramón Blanco, Mar Masiá, Elena Sendagorta, Gonzalo Sanz, Santiago Moreno, José A Pérez-Molina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5708629?pdf=render

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http://europepmc.org/articles/PMC5708629?pdf=render

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