Determination of the membrane topology of the small EF-hand Ca2+-sensing proteins CaBP7 and CaBP8.

The CaBPs represent a subfamily of small EF-hand containing calcium (Ca(2+))-sensing proteins related to calmodulin that regulate key ion channels in the mammalian nervous system. In a recent bioinformatic analyses we determined that CaBP7 and CaBP8 form an evolutionarily distinct branch within the...

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Bibliographic Details
Main Authors: Hannah V McCue, Robert D Burgoyne, Lee P Haynes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3062558?pdf=render