Minimal Purkinje Cell-Specific PCP2/L7 Promoter Virally Available for Rodents and Non-human Primates

Minimal Purkinje Cell-Specific PCP2/L7 Promoter Virally Available for Rodents and Non-human Primates

Cell-type-specific promoters in combination with viral vectors and gene-editing technology permit efficient gene manipulation in specific cell populations. Cerebellar Purkinje cells play a pivotal role in cerebellar functions. Although the Purkinje cell-specific L7 promoter is widely used for the ge...

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Bibliographic Details
Main Authors: Keisuke Nitta, Yasunori Matsuzaki, Ayumu Konno, Hirokazu Hirai
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
Purkinje cell
L7
PCP2
cerebellum
lentivirus
adeno-associated virus
viral vector
cell type-specific promoter
marmoset
non-human primate
Online Access:http://www.sciencedirect.com/science/article/pii/S232905011730089X

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http://www.sciencedirect.com/science/article/pii/S232905011730089X

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