Integration of single-cell RNA-seq data into population models to characterize cancer metabolism.

Integration of single-cell RNA-seq data into population models to characterize cancer metabolism.

Metabolic reprogramming is a general feature of cancer cells. Regrettably, the comprehensive quantification of metabolites in biological specimens does not promptly translate into knowledge on the utilization of metabolic pathways. By estimating fluxes across metabolic pathways, computational models...

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Bibliographic Details
Main Authors: Chiara Damiani, Davide Maspero, Marzia Di Filippo, Riccardo Colombo, Dario Pescini, Alex Graudenzi, Hans Victor Westerhoff, Lilia Alberghina, Marco Vanoni, Giancarlo Mauri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC6413955?pdf=render

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http://europepmc.org/articles/PMC6413955?pdf=render

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