Liver-specific transgenic expression of cholesteryl ester hydrolase reduces atherosclerosis in Ldlr−/− mice[S]

The liver plays a central role in the final elimination of cholesterol from the body either as bile acids or as free cholesterol (FC), and lipoprotein-derived cholesterol is the major source of total biliary cholesterol. HDL is the major lipoprotein responsible for removal and transport of cholester...

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Bibliographic Details
Main Authors: Jinghua Bie, Jing Wang, Quan Yuan, Genta Kakiyama, Siddhartha S. Ghosh, Shobha Ghosh
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520376616