Design and Development of a Novel Peptide for Treating Intestinal Inflammation

Design and Development of a Novel Peptide for Treating Intestinal Inflammation

Intestinal inflammatory disorders, such as inflammatory bowel disease (IBD), are associated with increased pro-inflammatory cytokine secretion in the intestines. Furthermore, intestinal inflammation increases the risk of enteric cancer, which is a common malignancy globally. Native anti-inflammatory...

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Bibliographic Details
Main Authors: Lulu Zhang, Xubiao Wei, Rijun Zhang, Jim N. Petitte, Dayong Si, Zhongxuan Li, Junhao Cheng, Mengsi Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
anti-inflammatory activity
toll-like receptor
molecular dynamics simulation
lipopolysaccharide neutralization
intestinal barrier
NF-κB
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01841/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01841/full

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