Estrogen receptor-mediated repression of human hepatic lipase gene transcription

Estrogen receptor-mediated repression of human hepatic lipase gene transcription

Estrogen replacement therapy in women decreases hepatic lipase (HL) activity, which may account for the associated increase in HDL cholesterol. To investigate whether estrogen decreases HL transcription, transient cotransfection assays with HL promoter and estrogen receptor-α (ERα) expression constr...

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Bibliographic Details
Main Authors: Daniel R. Jones, Robert J. Schmidt, Richard T. Pickard, Patricia S. Foxworthy, Patrick I. Eacho
Format: Article
Language:English
Published: Elsevier 2002-03-01
Series:Journal of Lipid Research
Subjects:
HepG2 cells
AP-1
phorbol ester
very low density apolipoprotein II
promoter regulation
17β-estradiol
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520301449

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http://www.sciencedirect.com/science/article/pii/S0022227520301449

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