Characterization of the finch embryo supports evolutionary conservation of the naive stage of development in amniotes

Innate pluripotency of mouse embryos transits from naive to primed state as the inner cell mass differentiates into epiblast. In vitro, their counterparts are embryonic (ESCs) and epiblast stem cells (EpiSCs), respectively. Activation of the FGF signaling cascade results in mouse ESCs differentiatin...

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Bibliographic Details
Main Authors: Siu-Shan Mak, Cantas Alev, Hiroki Nagai, Anna Wrabel, Yoko Matsuoka, Akira Honda, Guojun Sheng, Raj K Ladher
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/07178