Monomeric and dimeric CXCL8 are both essential for in vivo neutrophil recruitment.
Rapid mobilization of neutrophils from vasculature to the site of bacterial/viral infections and tissue injury is a critical step in successful resolution of inflammation. The chemokine CXCL8 plays a central role in recruiting neutrophils. A characteristic feature of CXCL8 is its ability to reversib...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-07-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2909905?pdf=render |