Meta-Analysis of Preclinical Studies of Fibrinolytic Therapy for Acute Lung Injury

Meta-Analysis of Preclinical Studies of Fibrinolytic Therapy for Acute Lung Injury

BackgroundAcute lung injury (ALI) is characterized by suppressed fibrinolytic activity in bronchoalveolar lavage fluid (BALF) attributed to elevated plasminogen activator inhibitor-1 (PAI-1). Restoring pulmonary fibrinolysis by delivering tissue-type plasminogen activator (tPA), urokinase plasminoge...

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Bibliographic Details
Main Authors: Cong Liu, Yana Ma, Zhenlei Su, Runzhen Zhao, Xiaoli Zhao, Hong-Guang Nie, Ping Xu, Lili Zhu, Mo Zhang, Xiumin Li, Xiaoju Zhang, Michael A. Matthay, Hong-Long Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
lung diseases
fibrinolytic agents
molecular therapy
interventions
preclinical study
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01898/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01898/full

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