The elevation of plasma concentrations of apoB-48-containing lipoproteins in familial hypercholesterolemia is independent of PCSK9 levels

Abstract Background Previous studies have reported high plasma concentrations of both intestinal apolipoprotein (apo) B-48-containing lipoproteins and PCSK9 in subjects with familial hypercholesterolemia (FH). However, the extent to which LDL receptor deficiency and PCSK9 levels influence plasma apo...

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Bibliographic Details
Main Authors: Jean-Philippe Drouin-Chartier, Jean-Charles Hogue, André J. Tremblay, Jean Bergeron, Benoît Lamarche, Patrick Couture
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Lipids in Health and Disease
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12944-017-0502-x