Dual pathway spindle assembly increases both the speed and the fidelity of mitosis

Summary Roughly half of all animal somatic cell spindles assemble by the classical prophase pathway, in which the centrosomes separate ahead of nuclear envelope breakdown (NEBD). The remainder assemble by the prometaphase pathway, in which the centrosomes separate following NEBD. Why cells use dual...

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Bibliographic Details
Main Authors: Kuniyoshi Kaseda, Andrew D. McAinsh, Robert A. Cross
Format: Article
Language:English
Published: The Company of Biologists 2011-10-01
Series:Biology Open
Online Access:http://bio.biologists.org/content/1/1/12