Dual pathway spindle assembly increases both the speed and the fidelity of mitosis
Summary Roughly half of all animal somatic cell spindles assemble by the classical prophase pathway, in which the centrosomes separate ahead of nuclear envelope breakdown (NEBD). The remainder assemble by the prometaphase pathway, in which the centrosomes separate following NEBD. Why cells use dual...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2011-10-01
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Series: | Biology Open |
Online Access: | http://bio.biologists.org/content/1/1/12 |