A mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by Luciferase imaging.

A mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by Luciferase imaging.

BACKGROUND: Osteosarcoma (OSA) is lethal when metastatic after chemotherapy and/or surgical treatment. Thus animal models are necessary to study the OSA metastatic spread and to validate novel therapies able to control the systemic disease. We report the development of a syngeneic (Balb/c) murine OS...

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Main Authors: Silvia Miretti, Ilaria Roato, Riccardo Taulli, Carola Ponzetto, Michele Cilli, Martina Olivero, Maria Flavia Di Renzo, Laura Godio, Adriana Albini, Paolo Buracco, Riccardo Ferracini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2265554?pdf=render

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http://europepmc.org/articles/PMC2265554?pdf=render

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