P2Y2R deficiency attenuates experimental autoimmune uveitis development.

P2Y2R deficiency attenuates experimental autoimmune uveitis development.

We aimed to study the role of the nucleotide receptor P2Y2R in the development of experimental autoimmune uveitis (EAU). EAU was induced in P2Y2+/+ and P2Y2-/- mice by immunization with IRBP peptide or by adoptive transfer of in vitro restimulated semi-purified IRBP-specific enriched T lymphocytes f...

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Bibliographic Details
Main Authors: Lia Judice M Relvas, Maya Makhoul, Remi Dewispelaere, Laure Caspers, Didier Communi, Jean-Marie Boeynaems, Bernard Robaye, Catherine Bruyns, François Willermain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4334221?pdf=render

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http://europepmc.org/articles/PMC4334221?pdf=render

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