Controversies Surrounding the Origin of Hepatocytes in Adult Livers and the in Vitro Generation or Propagation of HepatocytesSummary

Epithelial cells in the liver (known as hepatocytes) are high-performance engines of myriad metabolic functions and versatile responders to liver injury. As hepatocytes metabolize amino acids, alcohol, drugs, and other substrates, they produce and are exposed to a milieu of toxins and harmful byprod...

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Bibliographic Details
Main Authors: Nicole Min Qian Pek, Kevin J. Liu, Massimo Nichane, Lay Teng Ang
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X20301594