Synthesis and evaluation of arylamidine derivatives for new antimicrobial and cytotoxic activities

Synthesis and evaluation of arylamidine derivatives for new antimicrobial and cytotoxic activities

ABSTRACT A series of arylamidines 3a-j was designed, synthesized and investigated for antimicrobial activity. Structures of the compounds were confirmed by IR, 1H-NMR and 13C-NMR and a 2D spectroscopic study was performed. A preliminary screening of the antimicrobial tests clearly showed that three...

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Bibliographic Details
Main Authors: ZENAIDE S. MONTE, AMANDA M. SILVA, GLÁUCIA M.S. LIMA, TERESINHA G. DA SILVA, KARLA M.R. MARQUES, MARIA D. RODRIGUES, EMERSON P.S. FALCÃO, SEBASTIÃO J. MELO
Format: Article
Language:English
Published: Academia Brasileira de Ciências
Series:Anais da Academia Brasileira de Ciências
Subjects:
arylamidines
2D spectroscopy
gram-negative bacteria
yeast
cytotoxicity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000301051&lng=en&tlng=en

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