Total Flavonoids of Litchi Seed Attenuate Prostate Cancer Progression Via Inhibiting AKT/mTOR and NF-kB Signaling Pathways

Total Flavonoids of Litchi Seed Attenuate Prostate Cancer Progression Via Inhibiting AKT/mTOR and NF-kB Signaling Pathways

Litchi seeds have been traditionally used in Chinese herbal formula for urologic neoplasms including prostate cancer (PCa). However, the effective components of Litchi seeds and the mechanisms of their actions on PCa cell growth and metastasis remain unclear. In this study, we investigated the effec...

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Bibliographic Details
Main Authors: Ming Chang, Dan Zhu, Yanjiang Chen, Weiquan Zhang, Xi Liu, Xiao-Lan Li, Zhiping Cheng, Zhiheng Su, Jian Zhang, Yi Lu, Hongwei Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
total flavonoids of litchi seed
prostate cancer
apoptosis
proliferation
metastasis
Akt
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.758219/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.758219/full

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