Evaluation of arecoline hydrobromide toxicity after a 14-day repeated oral administration in Wistar rats.

A subchronic toxicity test was conducted in rats on the basis of a previous acute toxicity test to evaluate the safety of arecoline hydrobromide (Ah), to systematically study its pharmacological effects and to provide experimental support for a safe clinical dose. Eighty rats were randomly divided i...

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Bibliographic Details
Main Authors: Xiaojuan Wei, Jiyu Zhang, Jianrong Niu, Xuzheng Zhou, Jianyong Li, Bing Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4399984?pdf=render