Long-Lasting Sparks: Multi-Metastability and Release Competition in the Calcium Release Unit Network.

Calcium (Ca) sparks are elementary events of biological Ca signaling. A normal Ca spark has a brief duration in the range of 10 to 100 ms, but long-lasting sparks with durations of several hundred milliseconds to seconds are also widely observed. Experiments have shown that the transition from norma...

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Bibliographic Details
Main Authors: Zhen Song, Alain Karma, James N Weiss, Zhilin Qu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4701461?pdf=render