S-allylmercaptoglutathione Is a Substrate for Glutathione Reductase (E.C. 1.8.1.7) from Yeast (Saccharomyces cerevisiae)

S-allylmercaptoglutathione Is a Substrate for Glutathione Reductase (E.C. 1.8.1.7) from Yeast (Saccharomyces cerevisiae)

Allicin (diallylthiosulfinate) is a potent thiol reagent and natural defense substance produced by garlic (Allium sativum) tissues when damaged. Allicin acts as a redox toxin and oxidizes the cellular glutathione (GSH) pool producing S-allylmercaptoglutathione (GSSA). The cellular enzyme glutathione...

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Bibliographic Details
Main Authors: Tobias Horn, Wolfgang Bettray, Alan J. Slusarenko, Martin C. H. Gruhlke
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Antioxidants
Subjects:
allicin
thiosulfinate
garlic
glutathione reductase
Online Access:http://www.mdpi.com/2076-3921/7/7/86

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